How to replace the brake pads on Lexus RX350?

2016 and later Lexus models feature an electronic parking brake system, requiring activation of "pad replacement mode" using a Toyota techstream scan tool or equivalent before brake pad removal. This mode rotates the nut inside the rear caliper piston, allowing compression for new pads or brake disc installation. An alternative method is to unplug the parking brake actuators' electrical connector, grounding one terminal with a jumper wire while applying battery voltage to the other terminal, closely monitoring the piston to prevent outward movement (parking brake engagement). Ensure proper torque when reinstalling the caliper bolts, depress the brake pedal firmly to engage the pads with the disc, check and top up brake fluid as needed, and thoroughly test brake operation before returning the vehicle to normal service. For 2016 and later Lexus models, apply and release the parking brake multiple times to activate the caliper pistons and align them correctly during reassembly.

Genuine Lexus RX350 Brake Pad Set

Disc Brake Pad Set

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18 Brake Pad Sets found

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Lexus RX350 Rear Disc Brake Pad Kit
Part Number: 04466-0E060
$55.59 MSRP: $73.97
You Save: $18.38 (25%)
Ships in 1-3 Business Days
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Product Specifications
- Other Name: Pad Kit, Disc Brake, Rear; Brake Pads, Rear Pads
- Manufacturer Note: MARK AK NS554
- Position: Rear
- Warranty: This genuine part is guaranteed by Lexus's factory warranty.
Fits the following Vehicles:
- 2016-2022 Lexus RX350 | 6 Cyl 3.5L | 2GRFKS, 2GRFXS; 2GRFKS, 2GRFXS; GGL20L-CWZGBA, GGL25L-CWZGBA, GYL20L-CWXGBA, GYL25L-CWXGBA
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Lexus RX350 Front Disc Brake Pad Kit
Part Number: 04465-0E040
$75.36 MSRP: $101.91
You Save: $26.55 (27%)
Ships in 1-3 Business Days
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Product Specifications
- Other Name: Pad Kit, Disc Brake, Front; Brake Pads, Front Pads
- Manufacturer Note: MARK ADVICS PV565H
- Position: Front
- Warranty: This genuine part is guaranteed by Lexus's factory warranty.
Fits the following Vehicles:
- 2016-2020 Lexus RX350 | 6 Cyl 3.5L | 2GRFKS, 2GRFXS; 2GRFKS, 2GRFXS; GGL20L-CWZGBA, GGL25L-CWZGBA, GYL20L-CWXGBA, GYL25L-CWXGBA
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Lexus RX350 Front Disc Brake Pad Kit
Part Number: 04465-48150
$79.74 MSRP: $107.83
You Save: $28.09 (27%)
Ships in 1-3 Business Days
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Product Specifications
- Other Name: Pad Kit, Disc Brake, Front; Brake Pads, Front Pads
- Manufacturer Note: MARK ADVICS PV565H
- Position: Front
- Warranty: This genuine part is guaranteed by Lexus's factory warranty.
Fits the following Vehicles:
- 2010-2015 Lexus RX350 | STD | 6 Cyl 3.5L | 2GRFE, 2GRFXE; 2GRFE, 2GRFXE; GGL10L-AWTGKA, GGL15L-AWTGKA, GYL10L-AWXGKA, GYL15L-AWXGKA
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Lexus RX350 Rear Disc Brake Pad Kit
Part Number: 04466-0E010
$54.38 MSRP: $72.35
You Save: $17.97 (25%)
Ships in 1-3 Business Days
ADD TO CART
Product Specifications
- Other Name: Pad Kit, Disc Brake, Rear; Brake Pads, Rear Pads
- Manufacturer Note: MARK AK PA561
- Position: Rear
- Warranty: This genuine part is guaranteed by Lexus's factory warranty.
Fits the following Vehicles:
- 2010-2015 Lexus RX350 | STD | 6 Cyl 3.5L | 2GRFE, 2GRFXE; 2GRFE, 2GRFXE; GGL10L-CWTGKA, GGL15L-CWTGKA, GGL15L-CWZGKA, GYL10L-CWXGKA, GYL15L-CWXGKA
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Lexus RX350 Front Disc Brake Pad Kit
Part Number: 04465-0E010
$78.11 MSRP: $105.62
You Save: $27.51 (27%)
Ships in 1-3 Business Days
ADD TO CART
Product Specifications
- Other Name: Pad Kit, Disc Brake, Front; Brake Pads, Front Pads
- Manufacturer Note: MARK ADVICS PV565H
- Position: Front
- Warranty: This genuine part is guaranteed by Lexus's factory warranty.
Fits the following Vehicles:
- 2010-2015 Lexus RX350 | STD | 6 Cyl 3.5L | 2GRFE, 2GRFXE; 2GRFE, 2GRFXE; GGL10L-CWTGKA, GGL15L-CWTGKA, GGL15L-CWZGKA, GYL10L-CWXGKA, GYL15L-CWXGKA
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Lexus RX350 Front Disc Brake Pad Kit
Part Number: 04465-48100
$78.11 MSRP: $105.62
You Save: $27.51 (27%)
Ships in 1-3 Business Days
ADD TO CART
Product Specifications
- Other Name: Pad Kit, Disc Brake, Front; Brake Pads, Front Pads
- Manufacturer Note: MARK SUMITOMO PS558H
- Position: Front
- Warranty: This genuine part is guaranteed by Lexus's factory warranty.
Fits the following Vehicles:
- 2007-2009 Lexus RX350 | STD | 6 Cyl 3.3L, 6 Cyl 3.5L | 2GRFE, 3MZFE; 2GRFE, 3MZFE; GSU30L-AWAGKA, GSU30L-CWAGKA, GSU35L-AWAGKA, GSU35L-CWAGKA, MCU33L-AWAGKA, MCU33L-CWAGKA, MCU38L-AWAGKA, MCU38L-CWAGKA
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Lexus RX350 Rear Disc Brake Pad Kit
Part Number: 04466-48160
$57.49 MSRP: $76.50
You Save: $19.01 (25%)
Ships in 1-2 Business Days
ADD TO CART
Product Specifications
- Other Name: Pad Kit, Disc Brake, Rear; Brake Pads, Rear Pads
- Manufacturer Note: MARK AK NS554
- Position: Rear
- Warranty: This genuine part is guaranteed by Lexus's factory warranty.
Fits the following Vehicles:
- 2016-2022 Lexus RX350 | STD | 6 Cyl 3.5L | 2GRFKS, 2GRFXS; 2GRFKS, 2GRFXS; GGL25L-AWZGBA, GGL25L-BWZGBA, GYL25L-AWXGBA
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Lexus RX350 Rear Disc Brake Pad Kit
Part Number: 04466-48060
$54.99 MSRP: $73.17
You Save: $18.18 (25%)
Ships in 1-3 Business Days
ADD TO CART
Product Specifications
- Other Name: Pad Kit, Disc Brake, Rear; Brake Pads, Rear Pads
- Manufacturer Note: MARK AK PA561
- Position: Rear
- Replaces: 04466-48030
- Warranty: This genuine part is guaranteed by Lexus's factory warranty.
Fits the following Vehicles:
- 2007-2009 Lexus RX350 | STD | 6 Cyl 3.3L, 6 Cyl 3.5L | 2GRFE, 3MZFE; 2GRFE, 3MZFE; GSU30L-AWAGKA, GSU30L-CWAGKA, GSU35L-AWAGKA, GSU35L-CWAGKA, MCU33L-AWAGKA, MCU33L-CWAGKA, MCU38L-AWAGKA, MCU38L-CWAGKA
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Lexus RX350 Rear Disc Brake Pad Kit
Part Number: 04466-48130
$58.20 MSRP: $77.44
You Save: $19.24 (25%)
Ships in 1-3 Business Days
ADD TO CART
Product Specifications
- Other Name: Pad Kit, Disc Brake, Rear; Brake Pads, Rear Pads
- Manufacturer Note: MARK AK PA561
- Position: Rear
- Warranty: This genuine part is guaranteed by Lexus's factory warranty.
Fits the following Vehicles:
- 2010-2015 Lexus RX350 | STD | 6 Cyl 3.5L | 2GRFE, 2GRFXE; 2GRFE, 2GRFXE; GGL10L-AWTGKA, GGL15L-AWTGKA, GYL10L-AWXGKA, GYL15L-AWXGKA
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Lexus RX350 Front Disc Brake Pad Kit
Part Number: 04465-48210
$109.27 MSRP: $147.77
You Save: $38.50 (27%)
Ships in 1-3 Business Days
ADD TO CART
Product Specifications
- Other Name: Pad Kit, Disc Brake, Front; Brake Pads, Front Pads
- Manufacturer Note: MARK ADVICS PV565H
- Position: Front
- Warranty: This genuine part is guaranteed by Lexus's factory warranty.
Fits the following Vehicles:
- 2016-2020 Lexus RX350 | STD | 6 Cyl 3.5L | 2GRFKS, 2GRFXS; 2GRFKS, 2GRFXS; GGL25L-AWZGBA, GGL25L-BWZGBA, GYL25L-AWXGBA
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Lexus RX350 Disc Brake Pad Kit
Part Number: 04465-78010
$111.14 MSRP: $150.30
You Save: $39.16 (27%)
Ships in 1-3 Business Days
ADD TO CART
Product Specifications
- Other Name: Pad Kit, Disc Brake; Brake Pads, Front Pads
- Manufacturer Note: MARK ADVICS VC084H
- Position: Front
- Warranty: This genuine part is guaranteed by Lexus's factory warranty.
Fits the following Vehicles:
- 2019-2022 Lexus RX350 | STD | 6 Cyl 3.5L | 2GRFKS, 2GRFXS; 2GRFKS, 2GRFXS; GGL25L-AWZGBA, GGL25L-BWZGBA, GYL25L-AWXGBA
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Lexus RX350 Disc Brake Pad Kit
Part Number: 04465-02500
$117.43 MSRP: $158.80
You Save: $41.37 (27%)
Ships in 1-3 Business Days
ADD TO CART
Product Specifications
- Other Name: Pad Kit, Disc Brake; Brake Pads, Front Pads
- Manufacturer Note: MARK ADVICS VC084H
- Position: Front
- Warranty: This genuine part is guaranteed by Lexus's factory warranty.
Fits the following Vehicles:
- 2019-2022 Lexus RX350 | 6 Cyl 3.5L | 2GRFKS, 2GRFXS; 2GRFKS, 2GRFXS; GGL20L-CWZGBA, GGL25L-CWZGBA, GYL25L-CWXGBA
View related parts
Lexus RX350 PAD KIT, DISC BRAKE
Part Number: 04465-48270
$131.38 MSRP: $179.13
You Save: $47.75 (27%)
Ships in 1-2 Business Days
ADD TO CART
Product Specifications
- Other Name: Brake Pad, Front Pad
- Position: Front
- Warranty: This genuine part is guaranteed by Lexus's factory warranty.
Fits the following Vehicles:
- 2023-2025 Lexus RX350 | 4 Cyl 2.4L | T24AFTS; T24AFTS; TALA15L-CWZGTA, TALH17L-AWTGTA, TALH17L-CWTGTA
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Lexus RX350 PAD KIT, DISC BRAKE
Part Number: 04465-02530
$95.19 MSRP: $128.73
You Save: $33.54 (27%)
Ships in 1-2 Business Days
ADD TO CART
Product Specifications
- Other Name: Brake Pad, Front Pad
- Manufacturer Note: MARK ADVICS VC084H
- Position: Front
- Warranty: This genuine part is guaranteed by Lexus's factory warranty.
Fits the following Vehicles:
- 2023-2025 Lexus RX350 | 4 Cyl 2.4L, 4 Cyl 2.5L | A25AFXS, T24AFTS; A25AFXS, T24AFTS; AALH15L-CWXGBA, TALA10L-CWZGTA, TALA15L-CWZGTA
View related parts
Lexus RX350 PAD KIT, DISC BRAKE
Part Number: 04466-48170
$64.69 MSRP: $87.47
You Save: $22.78 (27%)
Ships in 1-2 Business Days
ADD TO CART
Product Specifications
- Other Name: Brake Pad
- Manufacturer Note: MARK NBK D6363-FF
- Position: Rear
- Warranty: This genuine part is guaranteed by Lexus's factory warranty.
Fits the following Vehicles:
- 2023-2025 Lexus RX350 | 4 Cyl 2.4L, 4 Cyl 2.5L | A25AFXS, T24AFTS; A25AFXS, T24AFTS; AALH15L-AWXGBA, AALH16L-AWXGBA, TALA10L-AWZGTA, TALH17L-AWTGTA, TALH17L-CWTGTA
View related parts
Lexus RX350 PAD KIT, DISC BRAKE
Part Number: 04466-02480
$66.11 MSRP: $89.41
You Save: $23.30 (27%)
Ships in 1-2 Business Days
ADD TO CART
Product Specifications
- Other Name: Brake Pad, Rear Pad
- Manufacturer Note: MARK NBK D6363-FF
- Position: Rear
- Warranty: This genuine part is guaranteed by Lexus's factory warranty.
Fits the following Vehicles:
- 2023-2025 Lexus RX350 | 4 Cyl 2.4L, 4 Cyl 2.5L | A25AFXS, T24AFTS; A25AFXS, T24AFTS; AALH15L-CWXGBA, TALA10L-CWZGTA, TALA15L-CWZGTA
View related parts
Lexus RX350 PAD KIT, DISC BRAKE
Part Number: 04465-48250
$115.68 MSRP: $156.44
You Save: $40.76 (27%)
Ships in 1-2 Business Days
ADD TO CART
Product Specifications
- Other Name: Brake Pad
- Manufacturer Note: MARK ADVICS VC084H
- Position: Front
- Warranty: This genuine part is guaranteed by Lexus's factory warranty.
Fits the following Vehicles:
- 2023-2025 Lexus RX350 | 4 Cyl 2.4L, 4 Cyl 2.5L | A25AFXS, T24AFTS; A25AFXS, T24AFTS; AALH15L-AWXGBA, TALA10L-AWZGTA
View related parts
Lexus RX350 PAD KIT, DISC BRAKE
Part Number: 04465-48260
$119.67 MSRP: $161.83
You Save: $42.16 (27%)
Ships in 1-2 Business Days
ADD TO CART
Product Specifications
- Other Name: Brake Pad
- Manufacturer Note: MARK ADVICS VC115
- Position: Front
- Warranty: This genuine part is guaranteed by Lexus's factory warranty.
Fits the following Vehicles:
- 2023-2025 Lexus RX350 | 4 Cyl 2.5L | A25AFXS; A25AFXS; AALH16L-AWXGBA

Lexus RX350 Brake Pad Set

Should you need to purchase new auto parts for your vehicle, we strongly suggest you consider the genuine Lexus RX350 Brake Pad Set available on LexusPartsNow.com. Our OEM Lexus RX350 Brake Pad Set come with the reassurance of the manufacturer's warranty, a hassle-free return policy, and speedy delivery service, all at affordable prices online. Feel free to shop with confidence!

Lexus RX350 Brake Pad Set Parts Questions & Experts Answers

Front Disc Brake Pad Kit
04465-48100
Q: How to replace the brake pads on Lexus RX350?
A: 2016 and later Lexus models feature an electronic parking brake system, requiring activation of "pad replacement mode" using a Toyota techstream scan tool or equivalent before brake pad removal. This mode rotates the nut inside the rear caliper piston, allowing compression for new pads or Brake Disc installation. An alternative method is to unplug the parking brake actuators' electrical connector, grounding one terminal with a jumper wire while applying battery voltage to the other terminal, closely monitoring the piston to prevent outward movement (parking brake engagement). Ensure proper torque when reinstalling the caliper bolts, depress the brake pedal firmly to engage the pads with the disc, check and top up brake fluid as needed, and thoroughly test brake operation before returning the vehicle to normal service. For 2016 and later Lexus models, apply and release the parking brake multiple times to activate the caliper pistons and align them correctly during reassembly.

Related Lexus RX350 Parts

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